Granuloma piógeno oral. Serie de casos / Oral pyogenic granuloma. Case series

RESUMEN El granuloma piógeno es una lesión que se manifiesta en la piel y en la cavidad oral, relacionado con diversas causas, como irritación crónica, trauma y cambios hormonales. Clínicamente se muestra como una lesión hiperplásica altamente vascularizada, con un tamaño de 1-3 cm, de base pedunculada o sésil y de crecimiento lento. Predomina en el sexo femenino y tiende a aparecer, sobre todo, en la encía, con muy pocos casos reportados en zonas edentes, motivo por el que se realizó el reporte de tres casos de granuloma piógeno oral en pacientes femeninas, comprendidas entre 30 y 40 años de edad. Se presentaron lesiones que diferían en cuanto a su localización y apariencia clínica (AU).

ABSTRACT Pyogenic granuloma is a lesion that arises in the skin and oral cavity, related to various causes, such as chronic irritation, trauma and hormonal changes. Clinically it looks like a highly vascularized hyperplastic lesion, sized 1-3 cm, with a pedunculated or sessile base and slow growing. It predominates in the female sex and tends to appear, above all, in the gum, with very few cases reported in edentulous areas; that is why the authors reported three cases of oral pyogenic granuloma in female patients, aged between 30 and 40 years. The lesions differed in their location and clinical appearance (AU).

Granuloma piógeno de localización atípica: reporte de un caso / Atypical location of a pyogenic granuloma: report of a case

El granuloma piógeno es una lesión que se manifiesta con frecuencia en piel y cavidad oral, está relacionado con diversas causas como irritación crónica, trauma y cambios hormonales. Clínicamente se muestra como una lesión hiperplásica altamente vascularizada de tamaño por lo regularmenor de 2 cm, de base pedunculada o sésil y de crecimiento lento. No tiene predilección por edad o sexo, tiende a aparecer sobre todo en la encía, labios y mucosa bucal, con muy pocos casos reportados en la región lingual, motivo por el que se lleva a cabo el presente reporte de caso, a fin de describir esta lesión en el tercio posterior del dorso delengua en un paciente de 85 años de edad.

Piogenyc granuloma is an injury commonly seen in the skin and oralcavity, it is related to several causes such as chronic irritation, traumaand hormonal changes. Clinically, it is presented as a hyperplasicinjury highly vascular-related, with a size generally no bigger than 2cm pedunculated in base or sessile and slow in growth. Without showingany preferece in age or gender, it tends to appear mainly on the gums,lips and oral mucosae, with very few reported cases in the lingual area.Therefore the hereby report is delivered as means to describe this kindof injury with a very unusual location.

A retrospective analysis of reactive hyperplastic lesions of the oral cavity: study of 1149 cases diagnosed between 2000 and 2011, Chile / Análisis retrospectivo de lesiones reaccionales hiperplásicas en mucosa oral: estudio de 1149 casos diagnosticados entre el 2000–2011 en chile

El objetivo de este estudio fue determinar la frecuencia relativa y distribución de lesiones reaccionales hiperplásicas (LRH) de la mucosa oral, presentes en el registro de biopsias del Servicio de Anatomía Patológica de la Facultad de Odontología, Universidad de Chile. Este estudio de tipo retrospectivo consistió en 1149 biopsias con diagnóstico histopatológico de LRH, entre los años 2000-2011. Las LRH se clasificaron en 5 grupos: Hiperplasia fibrosa (HF), granuloma piogénico (GP), granuloma periférico de células gigantes (GPCG) y fibroma osificante periférico(FOP). Los datos de edad y sexo de los sujetos, y de localización y tipo de lesión, fueron obtenidos del registro de biopsias de cada caso. De las LRH, la lesión más frecuente fue HF (71,1 por ciento), seguido de GP (21,1 por ciento), GPCG (5 por ciento) y FOP (2,9 por ciento) respectivamente. Las biopsias de LRH fueron mas frecuentes en mujeres (70,7 por ciento). El rango etario más afectado fue el de 50 a 59 años (22 por ciento). La localización de mayor frecuencia de LRH fue el maxilar superior (24,7 por ciento), seguida de mejilla (20,6 por ciento), lengua (19,4 por ciento), mandíbula (18,5 por ciento), labio inferior (9,9 por ciento) y labio superior (6,7 por ciento). En este estudio, de las LRH el diagnóstico más prevalente fue FH. El sexo más afectado fue el femenino, el rango etario el de 50 a 59 años y la ubicación más frecuente, maxilar superior. Estos resultados en general son concordantes con lo descrito en otros países.

The aim of this study was to determine the relative frequency and distribution of reactive hyperplastic lesions (RHL) of the oral mucosa at the Oral Pathology Institute of the School of Dentistry at the University of Chile. This was a retrospective study of 1149 biopsies with histopathological diagnosis of RHL, performed between 2000 and 2011. The RHL were classified in 4 groups: fibrous hyperplasia (FH), pyogenic granuloma (PG), peripheral giant-cell granuloma (PGCG) and peripheral ossifying fibroma (POF). Results: the most frequent RHL was FH (71. 1%), followed by PG (21.1%), PGCG (5 %) and POF (2.9%). RHLs were more frequent in women (70.7%). The most highly affected age group was the 50- to 59-year-olds (22%). The most frequent location for RHL was maxilla (24.7%), followed by cheek (20.6%), tongue (19.4%) and jaw (18.5%). The most prevalent RHL diagnosis was FH. Themost frequently affected sex was female, the most frequent agerange was 50-59 years, and the most frequent location, maxilla.

Oral granuloma gravidarum: a retrospective study of 41 cases in Southern Brazil

Granuloma gravidarum (GG) is an inflammatory lesion, which develops in the oral mucosa of pregnant women in response to chronic low-grade irritants, under the influence of hormonal factors. Objective To characterize GG clinically by means of a retrospective study of the cases of the Oral Medicine Division, São Lucas Hospital, Brazil. Material and Methods Cases of GG diagnosed between 1980 and 2012 were analyzed. Data were obtained referring to the age of the patients, lesion location, clinical features, as well as the presence of local irritants. The gestation period in which the lesion developed was also investigated. Results Forty-one cases of GG were found. The lesions developed predominantly in the third trimester of pregnancy (51.22%) and the mean age of the patients was 28 years. Most GG was found in the gingiva (73.17%), was reddish color and had a mean diameter of 1.5 cm. Local irritants were involved in 75.6% of the cases. Conclusions The hormonal conditions of pregnancy can have an impact on the oral cavity, predisposing the patient to inflammatory lesions such as GG. .

Granuloma piogênico oral: um estudo epidemiológico de 191 casos / Oral pyogenic granuloma: a epidemiologic study of 191 cases

Objetivos: Avaliar a prevalência do granuloma piogênico e comparar os dados obtidos com outros relatos na literatura mundial. Métodos: O material do estudo foi levantado a partir dos registros de pacientes com diagnóstico de granuloma piogênico oral no Laboratório de Patologia Oral da Faculdade de Odontologia, da Universidade de Pernambuco, no período de janeiro de 1992 a março de 2007 (15 anos). Foram analisados os indicadores gênero, faixa etária, raça, localização anatômica, diâmetro das lesões e presença de sintomatologia. Resultados: Dentre os 5007 registros presentes no laboratório, 3,81% correspondiam a lesões diagnosticadas como granuloma piogênico oral, onde 19,9% dos pacientes pertenciam a segunda década de vida, 40,1% eram da raça branca, a gengiva foi o local mais acometido (77,9%) e lesões de menor diâmetro (0,1 a 2 cm) foram as mais observadas no diagnóstico inicial. Conclusão: As características clínico-patológicas do granuloma piogênico oral na população estudada é similar aos outros estudos presentes na literatura.

Objectives: To evaluate the prevalence of pyogenic granuloma and compare the data obtained with those of other reports in the world literature. Methods: The study material was surveyed from the records of patients with diagnosis of oral pyogenic granuloma, at the Oral Pathology Laboratory of the School of Dentistry of the University of Pernambuco, in the period from January 1992 to March 2007 (15 years). The following indicators were analyzed: gender, age group, race, anatomic location, diameter of lesions and presence of symptomatology. Results: Among the 5007 records in the laboratory, 3.81% corresponded to lesions diagnosed as oral pyogenic granuloma, in which 19.9% of the patients were in the second decade of life, 40.1% were white, the gingiva was the most affected location (77.9%) and lesion of smaller diameter (0.1 to 2 cm) were those most observed at the initial diagnosis. Conclusion: The clinical-pathological characteristics of oral pyogenic granuloma in the studied population are similar to those of other studies in the literature.

[Prevalence of peripheral soft connective tissue lesions in patients referred to pathology department of Shahid Beheshti dental school, 1981-2006]

Peripheral soft connective tissue lesions are common in oral mucosa and despite their benign nature can make problems for patients. According to our knowledge, a comprehensive study for these lesions was not performed in Iran General practitioners are commonly encountered affected with these lesions. They have not enough information about their clinical prevalence, may make mistake in diagnosis and treatment plan. The aim of this study was to evaluate peripheral soft connective tissue lesions prevalence in patients referred to Pathology department of Shahid Beheshti Dental School during 1981-2006. In this descriptive retrospective study [existing data], cases were patients that referred to Pathology Dept. [1981-2006] with complete files recorded in the Dept. Questionnaires included age, sex, location of lesion and lesion type which were retrieved from patient's files. The incomplete files were excluded. Finally the collected data were analyzed descriptively by SPSS Ver 11.0 software. A total number of 900 cases had peripheral soft connective tissue lesions during 1981-2006 from 4529 files in the department. 29.7% [268 cases] were irritation fibroma, 21.9% [197 cases] were peripheral giant cell granuloma, 19.5% [176 cases] were pyogenic granuloma, 19.3% [174 cases] were epulis fissuratum, 8% [72 cases] were peripheral ossifying fibroma, 0.5% [5 cases] were giant cell fibroma, 0.4% [4 cases] were oral focal mucinosis and 0.4% were inflammatory papillary hyperplasia. The most prevalent age was 50-59 years [18.1%] and 20-29 years [16.3%]. The lesions were more prevalent in women [61.9%] and were 38.1% in men. The most prevalent site was gingival [54.3%] and the least prevalent site was floor of the mouth [0.1%]. 19.9% peripheral soft connective tissue lesions were reported, the most frequent lesion was irritation fibroma that was similar to other reports

Presentación inusual de un hemangioma capilar lobulado en paciente pediátrico: reporte de un caso y revisión de la literatura / Unusual presentation of a lobular capillary hemangioma in a pediatric patient: report of a case and review of the literature

El hemangioma es un tumor benigno compuesto por vasos sanguíneos, el cual histopatologicamente presenta 2 variantes: hemangioma capilar, formado por canales capilares de pequeño diametro; hemangioma cavernoso, formado por grandes senos sanguíneos dilatados con paredes delgadas. Se presentan con mayor frecuencia en el sexo femenino y por lo general aparece pocos días después del nacimiento. La localización más frecuente en cavidad bucal es en la mucosa de los labios, lengua y carrillo. La lesión puede involucionar de forma espontanea o ser eliminada quirúrgicamente, en caso de que la lesión interfiera con alguna función del organismo. Su etiología es desconocida. Se reporta un caso de un paciente de sexo femenino de 6 años de edad que presenta lesión tumoral asintomática de color rosado con áreas ulcerativas y eritematosas de aspecto liso y brillante en el maxilar superior derecho ocasionando asimetría facial en dicha zona, dificultando la fonación y deglución. Se realizó biopsia insicional de la lesión con un diagnostico provisional de granuloma piogénico, se obtuvo como el resultado histopatológico hemangioma capilar lobular

The hemangioma is a benign tomour formed by sanguineos vases, wich present: 2 variants. Capillary Hemangioma: formed by capillary canals of small diameter; Cavernous Hemangioma: formed by great expanded sanguineous sines with thin walls. In most of the cases affect the femine sex and usually it appears after its birth. In bucal cavity the most frequently localization is in mucous of Lips, Tongue and Carrillo. The lesion can go back in spontaneous form or can be eliminated by surgery in the case that lesion affects any process of the organism. Its origin is unknown.Report of a 6 years feminine sex case, with an asymptomatic tumoral lesion and pink color, ulcerative and erythemative areas, its aspect is smooth and brilliant, located in superior right maxilar, causing facial asymmetry in this place. It was done an incisional biopsy of the lesion and the provisional diagnostic was: Granuloma Pyogenic, and the histopatologic result was: Hemangioma Capilar Lobular.

Granuloma piogênico / Piogenic granulom

Neste trabalho, os autores realizaram uma revisão de literatura atualizada sobre um granuloma piogênico, e um estudo epidemiológico de 150 casos desta lesão dianosticados no período de 1970 a abril de 2002 no serviço da Disciplina de Patologia Oral, do Departamento de odontologia da UFRN. Dos 150 casos de granuloma piogênico em um total de 5.935 fichas, foram analisadas as variáveis gênero, idade, raça, implantação, diagnóstico clínico e localização anatômica, comparando-se também os dados obtidos com a literatura mundial pertinente

Granuloma piogénico: reporte de dos casos de aparición inusual y revisión de la literatura / Pyogenic granuloma: report of two cases and review of the literature

El granuloma piogénico es una lesión benigna, reactiva y multifactorial, que resulta de injurias repetitivas, microtraumatismo e irritación local sobre piel o membranas mucosas. Cuando aparece en la cavidad tiene predilección por la encía vestibular, pero es importante que el odontólogo esté en conocimiento y se familiarice con el hecho de que puede localizarse en otras zonas anatómicas, es por esto que hacemos referencia en el presente artículo de dos casos de localización inusual, conjuntamente con una revisión de la literatura

Granuloma piogênico: ocorrência, prevalência de gênero e de idade e aspectos clínicos mais comuns / Pyogenic granuloma: occurence, gender and age prevalence and common aspects

O granuloma piogênico pode ocorrer tanto em mucosa quanto em pele e apresenta uma grande incidência na cavidade bucal. Pacientes e clínicos que näo estäo familiarizados com esse tipo de lesäo, costumam ficar alarmados devido a sua rápida evoluçäo, vascularizaçäo e alto índice de recorrência quando a lesäo näo é totalmente removida. Este estudo baseou-se nos dados obtidos de prontuários do arquivo da Clínica de da Estomatologia da FOB-USP, no período de 1976 a 1998, onde se realizou uma análise da prevalência em relaçäo ao gênero, idade, local de maior ocorrência e aspectos clínicos